Lys117

Site Information
VLRPEIRkPEVLRPE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 150180304

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 2 ) , mass spectrometry ( 1 , 2 ) , mutation of modification site ( 2 ) , phospho-antibody ( 2 ) , western blotting ( 2 )
Disease tissue studied:	esophageal cancer ( 2 ) , esophageal carcinoma ( 2 )
Relevant cell line - cell type - tissue:	HEp-2 (squamous) ( 1 ) , Kyse30 (esophageal) ( 2 )

References
1	Akimov V, et al. (2018) UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites. Nat Struct Mol Biol 25, 631-640 29967540 Curated Info
2	Li Y, et al. (2017) The E3 ligase HECTD3 promotes esophageal squamous cell carcinoma (ESCC) growth and cell survival through targeting and inhibiting caspase-9 activation. Cancer Lett 404, 44-52 28716524 Curated Info