Lys100

Site Information
RQAAkLskPTLENLt SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 150180300

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 3 ) , mass spectrometry ( 1 , 3 ) , mutation of modification site ( 3 ) , phospho-antibody ( 3 ) , western blotting ( 3 )
Disease tissue studied:	esophageal cancer ( 3 ) , esophageal carcinoma ( 3 )
Relevant cell line - cell type - tissue:	HEp-2 (squamous) ( 1 ) , Kyse30 (esophageal) ( 3 )

References
1	Akimov V, et al. (2018) UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites. Nat Struct Mol Biol 25, 631-640 29967540 Curated Info
2	Lumpkin RJ, et al. (2017) Site-specific identification and quantitation of endogenous SUMO modifications under native conditions. Nat Commun 8, 1171 29079793 Curated Info
3	Li Y, et al. (2017) The E3 ligase HECTD3 promotes esophageal squamous cell carcinoma (ESCC) growth and cell survival through targeting and inhibiting caspase-9 activation. Cancer Lett 404, 44-52 28716524 Curated Info