Ser759
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Home > Phosphorylation Site Page: > Ser759  -  ITGB5 (human)

Site Information
REFAkFQsERsRARy   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 14694704

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
melanoma skin cancer ( 1 )
Relevant cell line - cell type - tissue:
CS-1 ( 1 )

Upstream Regulation
Putative in vivo kinases:
PAK4 (human) ( 1 )
Kinases, in vitro:
PAK4 (human) ( 1 )

Downstream Regulation
Effects of modification on biological processes:
cell motility, altered ( 1 )

References 

1

Li Z, et al. (2010) p21-activated kinase 4 phosphorylation of integrin beta5 Ser-759 and Ser-762 regulates cell migration. J Biol Chem 285, 23699-710
20507994   Curated Info

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