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Site Information |
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EKATGRYyAMKILKK SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 14515900 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
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Upstream Regulation | |
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Downstream Regulation | |
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Effects of modification on Akt1: | |
Effects of modification on biological processes: |
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Relevant diseases: |
References | |
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Yu X, et al. (2020) Combined inhibition of ACK1 and AKT shows potential toward targeted therapy against KRAS-mutant non-small-cell lung cancer. Bosn J Basic Med Sci
32530390 Curated Info |
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Zhang J, et al. (2015) PDGFR-β-activated ACK1-AKT Signaling Promotes Glioma Tumorigenesis. Int J Cancer 136, 1769-80
25257795 Curated Info |
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Mahajan K, et al. (2010) Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation. PLoS One 5, e9646
20333297 Curated Info |