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Home > Phosphorylation Site Page: > Tyr417  -  PKCZ (human)

Site Information
tFCGtPNyIAPEILR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 14305100

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Regulatory protein:
EGFR (human) ( 1 )
EGF ( 1 )

Downstream Regulation
Effects of modification on PKCZ:
enzymatic activity, induced ( 1 )



Valkova C, et al. (2010) Activation by tyrosine phosphorylation as a prerequisite for protein kinase Czeta to mediate epidermal growth factor receptor signaling to ERK. Mol Cancer Res 8, 783-97
20407013   Curated Info