Tyr859
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus®
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Tyr859  -  TrkC (rat)

Site Information
LGKATPIyLDILG__   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451749

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , peptide sequencing ( 1 ) , phospho-antibody ( 1 ) , phosphoamino acid analysis ( 1 ) , phosphopeptide mapping ( 1 )
Relevant cell line - cell type - tissue:
3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout] ( 1 )

Upstream Regulation
Treatments:
neurotrophin-3 ( 1 )

Downstream Regulation
Effects of modification on TrkC:
molecular association, regulation ( 1 )
Induce interaction with:
PLCG1 (mouse) ( 1 ) , SHC1 (mouse) ( 1 )

References 

1

Guiton M, et al. (1995) Naturally occurring tyrosine kinase inserts block high affinity binding of phospholipase C gamma and Shc to TrkC and neurotrophin-3 signaling. J Biol Chem 270, 20384-90
7657612   Curated Info