Ser720
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Home > Phosphorylation Site Page: > Ser720  -  BUB1B (human)

Site Information
TSENPTQsPWCSQYR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 13204438

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 2 ) , mass spectrometry ( 1 , 3 , 4 , 5 ) , mutation of modification site ( 2 , 5 ) , western blotting ( 2 )
Disease tissue studied:
cervical cancer ( 5 ) , cervical adenocarcinoma ( 5 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 1 , 2 , 3 ) , HeLa S3 (cervical) ( 5 ) , HeLa_BI (cervical) ( 4 ) , HeLa_Hesp (cervical) ( 4 )

Upstream Regulation
Treatments:
AZ3146 ( 2 ) , BI2536 ( 2 ) , SP600125 ( 2 ) , ZM447439 ( 2 )

References 

1

Sharma K, et al. (2014) Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Rep 8, 1583-94
25159151   Curated Info

2

Tipton AR, et al. (2013) Monopolar Spindle 1 (MPS1) Kinase Promotes Production of Closed MAD2 (C-MAD2) Conformer and Assembly of the Mitotic Checkpoint Complex. J Biol Chem 288, 35149-58
24151075   Curated Info

3

Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5
21712546   Curated Info

4

Hegemann B, et al. (2011) Systematic phosphorylation analysis of human mitotic protein complexes. Sci Signal 4, rs12
22067460   Curated Info

5

Elowe S, et al. (2010) Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1. J Cell Sci 123, 84-94
20016069   Curated Info