Thr236
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Home > Phosphorylation Site Page: > Thr236  -  CDC25C (human)

Site Information
VEKFKDNtIPDKVKK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451436

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 ) , peptide sequencing ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
CK2A1 (human) ( 1 )
Kinases, in vitro:
CK2A1 (human) ( 1 )
Treatments:
emodin ( 1 )

Downstream Regulation
Effects of modification on CDC25C:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Inhibit interaction with:
KPNB3 (human) ( 1 )

References 

1

Schwindling SL, Noll A, Montenarh M, Götz C (2004) Mutation of a CK2 phosphorylation site in cdc25C impairs importin alpha/beta binding and results in cytoplasmic retention. Oncogene 23, 4155-65
15064744   Curated Info