Lys855
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Home > Ubiquitylation Site Page: > Lys855  -  NFkB-p100 (human)

Site Information
RGPETRDkLPstAEV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 12723513

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 2 ) , mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Regulatory protein:
CUL1 (human) ( 2 ) , Nik (human) ( 2 ) , UBE2M (human) ( 2 )
Treatments:
siRNA ( 2 )

References 

1

Akimov V, et al. (2018) UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites. Nat Struct Mol Biol 25, 631-640
29967540   Curated Info

2

Amir RE, Haecker H, Karin M, Ciechanover A (2004) Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase. Oncogene 23, 2540-7
14676825   Curated Info