Ser21

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Home > Phosphorylation Site Page: > Ser21 - FBX46 (human)

Site Information
PRPFGTYsQNQPRPP SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1261736702

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 )
Disease tissue studied:	breast cancer ( 1 )
Relevant cell line - cell type - tissue:	MCF-7 (breast cell) ( 1 )

Downstream Regulation
Effects of modification on FBX46:	protein degradation ( 1 )

References
1	Choppara S, et al. (2018) The SCF ubiquitin ligase complex mediates degradation of the tumor suppressor FBXO31 and thereby prevents premature cellular senescence. J Biol Chem 30171069 Curated Info

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