Ser47
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.3
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser47  -  CDK5 (human)

Site Information
DDEGVPssALREICL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1255792403

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
CDK5 (human) ( 1 )
Kinases, in vitro:
CDK5 (human) ( 1 )

Downstream Regulation
Effects of modification on CDK5:
enzymatic activity, inhibited ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell growth, induced ( 1 ) , cell motility, inhibited ( 1 )
Inhibit interaction with:
CDK5R1 (human) ( 1 )

References 

1

Roach BL, et al. (2018) Identification and characterization of a novel phosphoregulatory site on cyclin-dependent kinase 5. Biochem Biophys Res Commun 504, 753-758
30217452   Curated Info