Ser304
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Home > Phosphorylation Site Page: > Ser304  -  CCNH (human)

Site Information
yEDDDyVsKKsKHEE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 12521707

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , phosphopeptide mapping ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
CDK8 (human) ( 2 )
Kinases, in vitro:
CDK8 (human) ( 2 )

Downstream Regulation
Effects of modification on biological processes:
cell growth, altered ( 2 ) , transcription, altered ( 2 )

References 

1

Guo A (2011) CST Curation Set: 11849; Year: 2011; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pTDXEAntibodies Used to Purify Peptides prior to LCMS: Phospho(Ser/Thr) CK2 Substrate (P-S/T3-100) Rabbit mAb Cat#: 8738
Curated Info

2

Akoulitchev S, Chuikov S, Reinberg D (2000) TFIIH is negatively regulated by cdk8-containing mediator complexes. Nature 407, 102-6
10993082   Curated Info