Ser454
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Home > Phosphorylation Site Page: > Ser454  -  EXO1 (human)

Site Information
SEGNKSLsFSEVFVP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1240800

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 ) , mutation of modification site ( 2 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 2 ) , Jurkat (T lymphocyte) ( 1 )

Upstream Regulation
Treatments:
hydroxyurea ( 2 )

Downstream Regulation
Effects of modification on EXO1:
protein degradation ( 2 )

References 

1

Mertins P, et al. (2013) Integrated proteomic analysis of post-translational modifications by serial enrichment. Nat Methods 10, 634-7
23749302   Curated Info

2

El-Shemerly M, et al. (2008) ATR-dependent pathways control hEXO1 stability in response to stalled forks. Nucleic Acids Res 36, 511-9
18048416   Curated Info

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