Ser303

Site Information
VITNRRKsGKYKKVE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 451171

In vivo Characterization
Methods used to characterize site in vivo:	[32P] bio-synthetic labeling ( 1 ) , mass spectrometry (in vitro) ( 2 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:	MTE4-14 ( 1 )

Downstream Regulation
Effects of modification on TACSTD2:	phosphorylation ( 1 ) , protein conformation ( 2 )
Effects of modification on biological processes:	carcinogenesis, induced ( 1 ) , cell growth, induced ( 1 ) , cytoskeletal reorganization ( 1 )

References
1	Guerra E, et al. (2022) Trop-2, Na/K ATPase, CD9, PKCα, cofilin assemble a membrane signaling super-complex that drives colorectal cancer growth and invasion. Oncogene 35132180 Curated Info
2	Pavšič M, et al. (2015) The cytosolic tail of the tumor marker protein Trop2 - a structural switch triggered by phosphorylation. Sci Rep 5, 10324 25981199 Curated Info
3	Basu A, Goldenberg DM, Stein R (1995) The epithelial/carcinoma antigen EGP-1, recognized by monoclonal antibody RS7-3G11, is phosphorylated on serine 303. Int J Cancer 62, 472-9 7635574 Curated Info