Thr1057
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Home > Phosphorylation Site Page: > Thr1057  -  ADCY2 (rat)

Site Information
QTLGYTCtCRGIINV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451157

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , immunoprecipitation ( 2 ) , mutation of modification site ( 1 ) , phospho-antibody ( 2 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 , 2 )

Upstream Regulation
Treatments:
H-89 ( 2 ) , phorbol_ester ( 2 )

Downstream Regulation
Effects of modification on ADCY2:
activity, induced ( 2 )

References 

1

Shen JX, et al. (2012) Muscarinic receptors stimulate AC2 by novel phosphorylation sites, whereas Gβγ subunits exert opposing effects depending on the G-protein source. Biochem J 447, 393-405
22906005   Curated Info

2

Böl GF, Hülster A, Pfeuffer T (1997) Adenylyl cyclase type II is stimulated by PKC via C-terminal phosphorylation. Biochim Biophys Acta 1358, 307-13
9366262   Curated Info

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