Tyr219
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Home > Phosphorylation Site Page: > Tyr219  -  MKK6 (human)

Site Information
IDAGCKPyMAPERIN   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1186001

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
RAW 264 (macrophage) ( 1 )

Upstream Regulation
Kinases, in vitro:
MKK6 (human) ( 1 )

Downstream Regulation
Effects of modification on MKK6:
molecular association, regulation ( 1 )
Induce interaction with:
RAC1 (human) ( 1 )

References 

1

Harraz MM, et al. (2007) MKK6 phosphorylation regulates production of superoxide by enhancing Rac GTPase activity. Antioxid Redox Signal 9, 1803-13
17854274   Curated Info