Ser191
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Home > Phosphorylation Site Page: > Ser191  -  CDC25C (human)

Site Information
EDQAEEIsDELMEFs   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450979

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
PLK3 (human) ( 2 )

Downstream Regulation
Effects of modification on CDC25C:
intracellular localization ( 2 )

References 

1

Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5
21712546   Curated Info

2

Bahassi el M, Hennigan RF, Myer DL, Stambrook PJ (2004) Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation. Oncogene 23, 2658-63
14968113   Curated Info