Ser102
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Home > Phosphorylation Site Page: > Ser102  -  MCL1 (mouse)

Site Information
SAAAAIVsPEEELDG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1172400

In vivo Characterization
Methods used to characterize site in vivo:
2D analysis ( 1 ) , [32P] ATP in vitro ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , spinal cord ( 1 )

Upstream Regulation
Putative in vivo kinases:
JNK3 (mouse) ( 1 )
Kinases, in vitro:
JNK3 (human) ( 1 )
Treatments:
anisomycin ( 1 ) , injury ( 1 )

Downstream Regulation
Effects of modification on MCL1:
molecular association, regulation ( 1 ) , protein degradation ( 1 )
Inhibit interaction with:
PIN1 (mouse) ( 1 )

References 

1

Li QM, et al. (2007) Opposite regulation of oligodendrocyte apoptosis by JNK3 and Pin1 after spinal cord injury. J Neurosci 27, 8395-404
17670986   Curated Info