Ser846
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Home > Phosphorylation Site Page: > Ser846  -  GluR6 (mouse)

Site Information
VGEFLYKsKKNAQLE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 11496000

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
'neuron, cortical' ( 1 ) , 'neuron, hippocampal' ( 1 ) , HeLa (cervical) ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKCA (human) ( 1 )
Kinases, in vitro:
PKCA (human) ( 1 )
Treatments:
phorbol_ester ( 1 )

Downstream Regulation
Effects of modification on GluR6:
intracellular localization ( 1 )
Effects of modification on biological processes:
endocytosis, altered ( 1 )

References 

1

Nasu-Nishimura Y, Jaffe H, Isaac JT, Roche KW (2010) Differential regulation of kainate receptor trafficking by phosphorylation of distinct sites on GluR6. J Biol Chem 285, 2847-56
19920140   Curated Info