Thr334
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Home > Phosphorylation Site Page: > Thr334  -  FPR1 (human)

Site Information
DstQtsDtAtNstLP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450843

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
neutrophil-blood ( 1 ) , U-937 (myeloid) ( 2 )

Upstream Regulation
Treatments:
cytochalasin_B ( 1 ) , fMLP ( 1 , 2 )

Downstream Regulation
Effects of modification on FPR1:
receptor desensitization, altered ( 2 ) , receptor internalization, altered ( 2 )

References 

1

Maaty WS, et al. (2013) Identification of C-terminal phosphorylation sites of N-formyl peptide receptor-1 (FPR1) in human blood neutrophils. J Biol Chem 288, 27042-58
23873933   Curated Info

2

Maestes DC, Potter RM, Prossnitz ER (1999) Differential phosphorylation paradigms dictate desensitization and internalization of the N-formyl peptide receptor. J Biol Chem 274, 29791-5
10514456   Curated Info