Lys191

Site Information
NVEKKIDkYTEVLKT SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 11317936
Available spectra: 2 CST

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 , 7 , 9 , 10 )
Disease tissue studied:	gastric cancer ( 5 ) , leukemia ( 9 ) , chronic myelogenous leukemia ( 9 ) , lung cancer ( 1 , 2 , 3 ) , non-small cell lung cancer ( 1 , 2 , 3 , 6 , 7 ) , non-small cell lung adenocarcinoma ( 1 , 2 ) , non-small cell large cell lung carcinoma ( 2 ) , non-small cell squamous cell lung carcinoma ( 7 )
Relevant cell line - cell type - tissue:	A549 (pulmonary) ( 10 ) , Calu-3 (pulmonary) ( 3 ) , DMS153 (pulmonary) ( 1 ) , HCC827 (pulmonary) ( 3 ) , HeLa (cervical) ( 4 ) , Jurkat (T lymphocyte) ( 10 ) , K562 (erythroid) ( 9 ) , lung ( 1 , 2 , 3 ) , MKN-45 (gastric) ( 5 ) , MV4-11 (macrophage) ( 10 ) , NCI-H1299 (pulmonary) ( 2 ) , NCI-H1437 (pulmonary) ( 1 ) , NCI-H1650 (pulmonary) ( 3 ) , NCI-H1703 (squamous) ( 7 ) , NCI-H1734 (pulmonary) ( 2 ) , NCI-H1944 (pulmonary) ( 2 ) , NCI-H1975 (pulmonary) ( 3 ) , NCI-H2073 (pulmonary) ( 1 ) , NCI-H209 (pulmonary) ( 1 ) , NCI-H2106 (pulmonary) ( 3 ) , NCI-H3255 (pulmonary) ( 6 ) , NCI-H358 (pulmonary) ( 2 ) , NCI-H460 (pulmonary) ( 2 ) , NCI-H838 (pulmonary) ( 1 )

References
1	Rikova K (2013) CST Curation Set: 20221; Year: 2013; Biosample/Treatment: cell line, H838, DMS153, H2073, H209, H1437; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
2	Rikova K (2013) CST Curation Set: 20216; Year: 2013; Biosample/Treatment: cell line, H1299, H1944, H358, H1734, H460; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
3	Rikova K (2013) CST Curation Set: 20217; Year: 2013; Biosample/Treatment: cell line, H1650, HCC827, H1975, Calu-3, H2106; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
4	Weinert BT, et al. (2013) Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation. Cell Rep 4, 842-51 23954790 Curated Info
5	Rikova K (2012) CST Curation Set: 16030; Year: 2012; Biosample/Treatment: cell line, MKN45/crizotinib; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
6	Rikova K (2012) CST Curation Set: 16031; Year: 2012; Biosample/Treatment: cell line, H3255/iressa; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
7	Rikova K (2012) CST Curation Set: 16032; Year: 2012; Biosample/Treatment: cell line, H1703/gleevec; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
8	Beli P, et al. (2012) Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response. Mol Cell 46, 212-25 22424773 Curated Info
9	Moritz A (2010) CST Curation Set: 9817; Year: 2010; Biosample/Treatment: cell line, K-562/untreated; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
10	Choudhary C, et al. (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325, 834-40 19608861 Curated Info