Lys88

Site Information
sLRQLAQkYNCDkMI SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 11315508
Available spectra: 1 CST

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 , 8 , 9 , 10 , 11 , 12 , 13 , 14 )
Disease tissue studied:	colorectal cancer ( 12 , 13 ) , colorectal carcinoma ( 12 , 13 ) , leukemia ( 8 , 9 , 10 , 11 ) , chronic myelogenous leukemia ( 8 , 9 , 10 , 11 ) , lung cancer ( 1 , 2 , 3 , 4 ) , non-small cell lung cancer ( 2 , 3 , 4 , 6 ) , non-small cell lung adenocarcinoma ( 1 , 2 , 3 , 4 ) , non-small cell large cell lung carcinoma ( 2 , 4 )
Relevant cell line - cell type - tissue:	A549 (pulmonary) ( 1 , 14 ) , Cal-12T (pulmonary) ( 3 ) , HCC44 (pulmonary) ( 3 ) , HCC78 (pulmonary) ( 2 ) , HCT116 (intestinal) ( 12 , 13 ) , Jurkat (T lymphocyte) ( 5 ) , K562 (erythroid) ( 8 , 9 , 10 , 11 ) , lung ( 2 , 3 , 4 ) , NCI-H1299 (pulmonary) ( 4 ) , NCI-H1437 (pulmonary) ( 3 ) , NCI-H1666 (pulmonary) ( 3 ) , NCI-H1734 (pulmonary) ( 4 ) , NCI-H1781 (pulmonary) ( 2 ) , NCI-H1944 (pulmonary) ( 4 ) , NCI-H2228 (pulmonary) ( 2 ) , NCI-H2405 (pulmonary) ( 3 ) , NCI-H3122 (pulmonary) ( 2 , 6 ) , NCI-H358 (pulmonary) ( 4 ) , NCI-H460 (pulmonary) ( 4 ) , NCI-H661 (pulmonary) ( 2 )

References
1	Wu Q, et al. (2015) Suberoylanilide hydroxamic acid treatment reveals crosstalks among proteome, ubiquitylome and acetylome in non-small cell lung cancer A549 cell line. Sci Rep 5, 9520 25825284 Curated Info
2	Rikova K (2013) CST Curation Set: 20219; Year: 2013; Biosample/Treatment: cell line, H2228, H3122, HCC78, H661, H1781; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
3	Rikova K (2013) CST Curation Set: 20220; Year: 2013; Biosample/Treatment: cell line, H1666, CAL-12T, H2405, HCC44, H1437; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
4	Rikova K (2013) CST Curation Set: 20216; Year: 2013; Biosample/Treatment: cell line, H1299, H1944, H358, H1734, H460; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
5	Mertins P, et al. (2013) Integrated proteomic analysis of post-translational modifications by serial enrichment. Nat Methods 10, 634-7 23749302 Curated Info
6	Rikova K (2013) CST Curation Set: 18855; Year: 2013; Biosample/Treatment: cell line, H3122/crizotinib, geldanamycin; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
7	Beli P, et al. (2012) Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response. Mol Cell 46, 212-25 22424773 Curated Info
8	Moritz A (2010) CST Curation Set: 9818; Year: 2010; Biosample/Treatment: cell line, K-562/untreated; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
9	Moritz A (2010) CST Curation Set: 9817; Year: 2010; Biosample/Treatment: cell line, K-562/untreated; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
10	Moritz A (2010) CST Curation Set: 9820; Year: 2010; Biosample/Treatment: cell line, K-562/untreated; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
11	Moritz A (2010) CST Curation Set: 9819; Year: 2010; Biosample/Treatment: cell line, K-562/untreated; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
12	Moritz A (2010) CST Curation Set: 9796; Year: 2010; Biosample/Treatment: cell line, HCT 116/untreated; Disease: colorectal carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
13	Moritz A (2010) CST Curation Set: 9797; Year: 2010; Biosample/Treatment: cell line, HCT 116/untreated; Disease: colorectal carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
14	Choudhary C, et al. (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325, 834-40 19608861 Curated Info