Tyr126

Site Information
ktDEGIAyrGLFIID SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 11059412
Available spectra: 1 CST

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 )
Disease tissue studied:	breast cancer ( 4 ) , lung cancer ( 2 ) , non-small cell lung cancer ( 2 , 3 ) , non-small cell lung adenocarcinoma ( 2 )
Relevant cell line - cell type - tissue:	BT-474 (breast cell) ( 4 ) , Cal-12T (pulmonary) ( 2 ) , HCC44 (pulmonary) ( 2 ) , HEK293T (epithelial) ( 1 ) , lung ( 2 ) , NCI-H1437 (pulmonary) ( 2 ) , NCI-H1666 (pulmonary) ( 2 ) , NCI-H2405 (pulmonary) ( 2 ) , NCI-H3122 (pulmonary) ( 3 )

References
1	Franchin C, et al. (2015) Quantitative analysis of a phosphoproteome readily altered by the protein kinase CK2 inhibitor quinalizarin in HEK-293T cells. Biochim Biophys Acta 1854, 609-23 25278378 Curated Info
2	Rikova K, Hall B (2013) CST Curation Set: 20741, 21168, 30173, 30174, 30175; Year: 2013; Biosample/Treatment: cell line, H1666, CAL-12T, H2405, HCC44, H1437; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P Curated Info
3	Rikova K (2013) CST Curation Set: 18450; Year: 2013; Biosample/Treatment: cell line, H3122/crizotinib, geldanamycin; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) MultiMab(TM) Rabbit mAb mix Cat#: 8954 Curated Info
4	Moritz A (2009) CST Curation Set: 7219; Year: 2009; Biosample/Treatment: cell line, BT-474/serum starved; Disease: breast cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info