Thr840
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Home > Phosphorylation Site Page: > Thr840  -  mGluR5 (rat)

Site Information
RSAFTTstVVRMHVG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450487

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 , 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on mGluR5:
activity, inhibited ( 1 ) , receptor inactivation, altered ( 2 )

References 

1

Uchino M, et al. (2004) Isoform-specific phosphorylation of metabotropic glutamate receptor 5 by protein kinase C (PKC) blocks Ca2+ oscillation and oscillatory translocation of Ca2+-dependent PKC. J Biol Chem 279, 2254-61
14561742   Curated Info

2

Sorensen SD, Conn PJ (2003) G protein-coupled receptor kinases regulate metabotropic glutamate receptor 5 function and expression. Neuropharmacology 44, 699-706
12681368   Curated Info