Lys88

Site Information
NRktLEGkVskrkAV SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 10769110

In vivo Characterization
Methods used to characterize site in vivo:	flow cytometry ( 1 ) , immunoassay ( 3 ) , mass spectrometry ( 1 , 2 ) , mass spectrometry (in vitro) ( 3 ) , modification-specific antibody ( 3 ) , western blotting ( 3 )
Relevant cell line - cell type - tissue:	spermatocytes ( 3 ) , testis ( 1 , 2 )

Downstream Regulation
Effects of modification on TP2:	molecular association, regulation ( 3 )
Effects of modification on biological processes:	chromatin organization, altered ( 3 )
Inhibit interaction with:	NPM3 (rat) ( 3 )

References
1	Gupta N, Madapura MP, Bhat UA, Rao MR (2015) Mapping of Post-translational Modifications of Transition Proteins, TP1 and TP2, and Identification of Protein Arginine Methyltransferase 4 and Lysine Methyltransferase 7 as Methyltransferase for TP2. J Biol Chem 290, 12101-22 25818198 Curated Info
2	Lundby A, et al. (2012) Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Cell Rep 2, 419-31 22902405 Curated Info
3	Pradeepa MM, et al. (2009) Acetylation of transition protein 2 (TP2) by KAT3B (p300) alters its DNA condensation property and interaction with putative histone chaperone NPM3. J Biol Chem 284, 29956-67 19710011 Curated Info