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Site Information |
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GHItTtPtPtQFLCP SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 450449 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Disease tissue studied: | |
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Upstream Regulation | |
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Downstream Regulation | |
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Effects of modification on Jun: | |
Effects of modification on biological processes: | |
Inhibit interaction with: |
References | |
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Waudby CA, et al. (2022) An intrinsic temporal order of c-JUN N-terminal phosphorylation regulates its activity by orchestrating co-factor recruitment. Nat Commun 13, 6133
36253406 Curated Info |
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Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62
27251275 Curated Info |
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Beli P, et al. (2012) Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response. Mol Cell 46, 212-25
22424773 Curated Info |
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Li T, et al. (2011) P21-activated protein kinase (PAK2)-mediated c-Jun phosphorylation at 5 threonine sites promotes cell transformation. Carcinogenesis 32, 659-66
21177766 Curated Info |
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Madeo A, et al. (2010) c-Jun activation is required for 4-hydroxytamoxifen-induced cell death in breast cancer cells. Oncogene 29, 978-91
19935718 Curated Info |
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Vinciguerra M, et al. (2008) Negative charged threonine 95 of c-Jun is essential for c-Jun N-terminal kinase-dependent phosphorylation of threonine 91/93 and stress-induced c-Jun biological activity. Int J Biochem Cell Biol 40, 307-16
17920329 Curated Info |
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Weiss C, et al. (2003) JNK phosphorylation relieves HDAC3-dependent suppression of the transcriptional activity of c-Jun. EMBO J 22, 3686-95
12853483 Curated Info |
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Ui M, et al. (1998) Biochemical and functional analysis of highly phosphorylated forms of c-Jun protein. FEBS Lett 429, 289-94
9662434 Curated Info |
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Papavassiliou AG, Treier M, Bohmann D (1995) Intramolecular signal transduction in c-Jun. EMBO J 14, 2014-9
7744008 Curated Info |