Ser303

Site Information
PEGEKLHsDsGIsVD SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 10432300

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:	brain cancer ( 1 ) , glioblastoma ( 1 ) , glioma ( 1 )
Relevant cell line - cell type - tissue:	brain ( 1 ) , U87MG (glial) ( 1 )

Downstream Regulation
Effects of modification on NGFR:	intracellular localization ( 2 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:	carcinogenesis, induced ( 1 ) , cell growth, altered ( 2 ) , cytoskeletal reorganization ( 2 )
Induce interaction with:	CLIM1 (human) ( 1 )

References
1	Ahn BY, et al. (2016) Glioma invasion mediated by the p75 neurotrophin receptor (p75(NTR)/CD271) requires regulated interaction with PDLIM1. Oncogene 35, 1411-22 26119933 Curated Info
2	Higuchi H, Yamashita T, Yoshikawa H, Tohyama M (2003) PKA phosphorylates the p75 receptor and regulates its localization to lipid rafts. EMBO J 22, 1790-800 12682012 Curated Info