Tyr367
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Home > Phosphorylation Site Page: > Tyr367  -  HIPK2 (human)

Site Information
tyLQsRYyRAPEIIL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1033356

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
liver cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
Abl (human) ( 1 )

Downstream Regulation
Effects of modification on HIPK2:
intracellular localization ( 1 ) , protein stabilization ( 1 )
Effects of modification on biological processes:
apoptosis, induced ( 1 ) , transcription, induced ( 1 )

References 

1

Reuven N, et al. (2015) The Tyrosine Kinase c-Abl Promotes Homeodomain-interacting Protein Kinase 2 (HIPK2) Accumulation and Activation in Response to DNA Damage. J Biol Chem 290, 16478-88
25944899   Curated Info