Ser983
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.2
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser983  -  Met (mouse)

Site Information
PHLDRLVsARSVsPT   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450188

In vivo Characterization
Methods used to characterize site in vivo:
phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
neuron ( 1 )

Upstream Regulation
Regulatory protein:
HGF (human) ( 1 )
Putative upstream phosphatases:
PPP2CA (mouse) ( 1 )

Downstream Regulation
Effects of modification on Met:
enzymatic activity, inhibited ( 1 )

Disease / Diagnostics Relevance
Relevant diseases:
ALS ( 1 )

References 

1

Kadoyama K, et al. (2009) Disease-dependent reciprocal phosphorylation of serine and tyrosine residues of c-Met/HGF receptor contributes disease retardation of a transgenic mouse model of ALS. Neurosci Res 65, 194-200
19595710   Curated Info