Ser2
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.6.0.2
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser2  -  PLD1 iso2 (rat)

Site Information
______MsLRSEARV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448572

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 , 2 ) , electrophoretic mobility shift ( 1 ) , mutation of modification site ( 1 , 2 ) , peptide sequencing ( 2 ) , phosphopeptide mapping ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PKCA (rat) ( 2 )
Kinases, in vitro:
PKCA (rat) ( 2 )
Phosphatases, in vitro:
PPP1CA (rat) ( 1 )
Treatments:
GF109203X ( 2 ) , phorbol_ester ( 1 , 2 ) , Ro31-8220 ( 2 )

Downstream Regulation
Effects of modification on PLD1 iso2:
enzymatic activity, induced ( 1 , 2 )

References 

1

Kim Y, et al. (2000) Phospholipase D1 is phosphorylated and activated by protein kinase C in caveolin-enriched microdomains within the plasma membrane. J Biol Chem 275, 13621-7
10788479   Curated Info

2

Kim Y, et al. (1999) Phosphorylation and activation of phospholipase D1 by protein kinase C in vivo: determination of multiple phosphorylation sites. Biochemistry 38, 10344-51
10441128   Curated Info