Ser364
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Home > Phosphorylation Site Page: > Ser364  -  GJA1 (mouse)

Site Information
AIVDQRPssRAssRA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450183

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 2 , 3 ) , mutation of modification site ( 4 ) , phospho-antibody ( 1 , 4 ) , western blotting ( 1 , 4 )
Relevant cell line - cell type - tissue:
'heart, ventricle' ( 1 ) , heart ( 2 , 3 ) , HeLa (cervical) ( 4 ) , MDCK (epithelial) ( 4 )

Upstream Regulation
Phosphatases, in vitro:
PPP3CB (mouse) ( 1 )

Downstream Regulation
Effects of modification on GJA1:
intracellular localization ( 4 ) , protein conformation ( 4 )

References 

1

Fontes MS, et al. (2014) Changes in Cx43 and NaV1.5 expression precede the occurrence of substantial fibrosis in calcineurin-induced murine cardiac hypertrophy. PLoS One 9, e87226
24498049   Curated Info

2

Lundby A, et al. (2013) In vivo phosphoproteomics analysis reveals the cardiac targets of β-adrenergic receptor signaling. Sci Signal 6, rs11
23737553   Curated Info

3

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

4

Sosinsky GE, et al. (2007) The C-terminus of connexin43 adopts different conformations in the Golgi and gap junction as detected with structure-specific antibodies. Biochem J 408, 375-85
17714073   Curated Info