Ser3

Site Information
_____MGsPLRFDGR SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 481131

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 2 , 3 , 4 , 5 , 6 )
Disease tissue studied:	breast cancer ( 2 , 4 ) , breast ductal carcinoma ( 2 ) , breast cancer, triple negative ( 2 ) , lung cancer ( 4 ) , non-small cell lung cancer ( 4 ) , ovarian cancer ( 2 )
Relevant cell line - cell type - tissue:	breast ( 2 ) , BT-549 (breast cell) ( 4 ) , Calu 6 (pulmonary) ( 4 ) , H2009 (pulmonary) ( 4 ) , H2077 (pulmonary) ( 4 ) , H2887 (pulmonary) ( 4 ) , H322M (pulmonary) ( 4 ) , HCC1359 (pulmonary) ( 4 ) , HCC1937 (breast cell) ( 4 ) , HCC2279 (pulmonary) ( 4 ) , HCC366 (pulmonary) ( 4 ) , HCC4006 (pulmonary) ( 4 ) , HCC78 (pulmonary) ( 4 ) , HCC827 (pulmonary) ( 4 ) , HOP62 (pulmonary) ( 4 ) , HUES-9 ('stem, embryonic') ( 5 ) , Jurkat (T lymphocyte) ( 3 ) , LCLC-103H (pulmonary) ( 4 ) , LOU-NH91 (squamous) ( 4 ) , MCF-7 (breast cell) ( 4 ) , MDA-MB-231 (breast cell) ( 4 ) , MV4-11 (macrophage) ( 6 ) , NCI-H1395 (pulmonary) ( 4 ) , NCI-H1568 (pulmonary) ( 4 ) , NCI-H157 (pulmonary) ( 4 ) , NCI-H1648 (pulmonary) ( 4 ) , NCI-H1666 (pulmonary) ( 4 ) , NCI-H2030 (pulmonary) ( 4 ) , NCI-H2172 (pulmonary) ( 4 ) , NCI-H322 (pulmonary) ( 4 ) , NCI-H460 (pulmonary) ( 4 ) , NCI-H520 (squamous) ( 4 ) , NCI-H647 (pulmonary) ( 4 ) , ovary ( 2 ) , PC9 (pulmonary) ( 4 )

References
1	Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62 27251275 Curated Info
2	Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704 24719451 Curated Info
3	Mertins P, et al. (2013) Integrated proteomic analysis of post-translational modifications by serial enrichment. Nat Methods 10, 634-7 23749302 Curated Info
4	Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68 22617229 Curated Info
5	Rigbolt KT, et al. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. Sci Signal 4, rs3 21406692 Curated Info
6	Oppermann FS, et al. (2009) Large-scale proteomics analysis of the human kinome. Mol Cell Proteomics 8, 1751-64 19369195 Curated Info