Thr538
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Home > Phosphorylation Site Page: > Thr538  -  TAK1 (human)

Site Information
QEYMKVQtEIALLLQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 971232900

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
acute myelogenous leukemia ( 1 ) , lymphoma ( 1 ) , T cell lymphoma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
calyculin_A ( 1 )

Downstream Regulation
Effects of modification on TAK1:
molecular association, regulation ( 1 )
Induce interaction with:
IKKG (human) ( 1 )

References 

1

Gallardo F, et al. (2018) Novel phosphorylated TAK1 species with functional impact on NF-κB and β-catenin signaling in human Cutaneous T-cell lymphoma. Leukemia
29511289   Curated Info