Ser1279
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Home > Phosphorylation Site Page: > Ser1279  -  APC (human)

Site Information
sRCSSLssLSSAEDE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450136

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , SW480 (intestinal) ( 1 )

Upstream Regulation
Putative in vivo kinases:
CK1E (human) ( 1 )

Downstream Regulation
Effects of modification on APC:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, altered ( 1 )
Induce interaction with:
CTNNB1 (human) ( 1 )

References 

1

Rubinfeld B, Tice DA, Polakis P (2001) Axin-dependent phosphorylation of the adenomatous polyposis coli protein mediated by casein kinase 1epsilon. J Biol Chem 276, 39037-45
11487578   Curated Info

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