Ser432

Site Information
DAsPGRGsHGQtPsP SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 481001

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 2 , 3 )
Disease tissue studied:	hepatocellular carcinoma, surrounding tissue ( 3 ) , major depressive disorder ( 2 )
Relevant cell line - cell type - tissue:	'brain, cerebral cortex' ( 2 ) , hepatic-'liver, para-hepatocellular carcinoma tissue' ( 3 )

Disease / Diagnostics Relevance
Relevant diseases:	major depressive disorder ( 2 )

References
1	Shiromizu T, et al. (2013) Identification of missing proteins in the neXtProt database and unregistered phosphopeptides in the PhosphoSitePlus database as part of the Chromosome-centric Human Proteome Project. J Proteome Res 12, 2414-21 23312004 Curated Info
2	Martins-de-Souza D, et al. (2012) Phosphoproteomic differences in major depressive disorder postmortem brains indicate effects on synaptic function. Eur Arch Psychiatry Clin Neurosci 262, 657-66 22350622 Curated Info
3	Gu T (2009) CST Curation Set: 6577; Year: 2009; Biosample/Treatment: liver, para-hepatocellular carcinoma tissue, hepatic/untreated; Disease: liver cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info