Ser246
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Home > Phosphorylation Site Page: > Ser246  -  ADRB2 (mouse)

Site Information
RFHAQNLsQVEQDGR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 481741

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 3 )
Disease tissue studied:
melanoma skin cancer ( 3 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 2 ) , skin [mGluR1 (mouse), transgenic, TG mutant mice] ( 3 )

Upstream Regulation
Treatments:
insulin ( 2 ) , LY294002 ( 2 ) , MK-2206 ( 2 )

References 

1

Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704
24719451   Curated Info

2

Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info

3

Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26
19367708   Curated Info