Ser455

Site Information
PVkTLPFsPSQFLNF SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 450114

In vivo Characterization
Methods used to characterize site in vivo:	[32P] bio-synthetic labeling ( 2 ) , immunoprecipitation ( 2 ) , mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , peptide sequencing ( 2 ) , phosphoamino acid analysis ( 2 )
Relevant cell line - cell type - tissue:	C3H10T1/2 (fibroblast) [FGFR2 (mouse), FGFR2 K668E] ( 1 ) , COS (fibroblast) ( 2 ) , HEK293T (epithelial) ( 2 )

Upstream Regulation
Kinases, in vitro:	CDK2 (mouse) ( 2 )

References
1	Li Y (2008) CST Curation Set: 5591; Year: 2008; Biosample/Treatment: cell line, 10T1/2FGFRK668E/FGF; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: PXpSP, pSPX(K/R) Antibodies Used to Purify Peptides prior to LCMS: Phospho-MAPK/CDK Substrates (PXSP or SPXR/K) (34B2) Rabbit mAb Cat#: 2325, PTMScan(R) Phospho-MAPK/CDK Substrate Motif (PXSP, SPXK/R) Immunoaffinity Beads Cat#: 1982 Curated Info
2	Johnson TK, Schweppe RE, Septer J, Lewis RE (1999) Phosphorylation of B-Myb regulates its transactivation potential and DNA binding. J Biol Chem 274, 36741-9 10593981 Curated Info

References

Li Y (2008) CST Curation Set: 5591; Year: 2008; Biosample/Treatment: cell line, 10T1/2FGFRK668E/FGF; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: PXpSP, pSPX(K/R) Antibodies Used to Purify Peptides prior to LCMS: Phospho-MAPK/CDK Substrates (PXSP or SPXR/K) (34B2) Rabbit mAb Cat#: 2325, PTMScan(R) Phospho-MAPK/CDK Substrate Motif (PXS*P, S*PXK/R) Immunoaffinity Beads Cat#: 1982
Curated Info

Johnson TK, Schweppe RE, Septer J, Lewis RE (1999) Phosphorylation of B-Myb regulates its transactivation potential and DNA binding. J Biol Chem 274, 36741-9
10593981 Curated Info