Thr524
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Home > Phosphorylation Site Page: > Thr524  -  B-Myb (mouse)

Site Information
DNtPHtPtPFKNALE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450112

In vivo Characterization
Methods used to characterize site in vivo:
2D analysis ( 2 ) , [32P] bio-synthetic labeling ( 1 , 2 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , peptide sequencing ( 1 ) , phosphoamino acid analysis ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 2 ) , COS (fibroblast) ( 1 ) , HEK293T (epithelial) ( 1 )

Upstream Regulation
Kinases, in vitro:
CDK2 (mouse) ( 1 )

Downstream Regulation
Effects of modification on B-Myb:
activity, induced ( 2 )
Effects of modification on biological processes:
transcription, induced ( 2 )

References 

1

Johnson TK, Schweppe RE, Septer J, Lewis RE (1999) Phosphorylation of B-Myb regulates its transactivation potential and DNA binding. J Biol Chem 274, 36741-9
10593981   Curated Info

2

Bartsch O, et al. (1999) Identification of cyclin A/Cdk2 phosphorylation sites in B-Myb. Eur J Biochem 260, 384-91
10095772   Curated Info

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