Tyr340
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Home > Phosphorylation Site Page: > Tyr340  -  DBNL (mouse)

Site Information
QTEEEPTyEVPPEQD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450090

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 , 2 , 3 ) , western blotting ( 1 , 2 , 3 )
Disease tissue studied:
lymphoma ( 3 ) , B cell lymphoma ( 3 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
Fyn (human) ( 1 )
Kinases, in vitro:
BLK (human) ( 3 ) , LYN (human) ( 3 ) , Syk (human) ( 3 )
Treatments:
vanadate ( 3 )

Downstream Regulation
Effects of modification on biological processes:
cell motility, induced ( 1 ) , cell motility, inhibited ( 2 ) , cytoskeletal reorganization ( 2 )

References 

1

Inoue S, et al. (2018) Drebrin-like (Dbnl) controls neuronal migration via regulating N-cadherin expression in the developing cerebral cortex. J Neurosci
30504273   Curated Info

2

Boateng LR, Cortesio CL, Huttenlocher A (2012) Src-mediated phosphorylation of mammalian Abp1 (DBNL) regulates podosome rosette formation in transformed fibroblasts. J Cell Sci 125, 1329-41
22303001   Curated Info

3

Larbolette O, et al. (1999) SH3P7 is a cytoskeleton adapter protein and is coupled to signal transduction from lymphocyte antigen receptors. Mol Cell Biol 19, 1539-46
9891087   Curated Info