Ser194

Site Information
LTKTAsEsIsNLsEA SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 468616

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 )
Relevant cell line - cell type - tissue:	'kidney, inner medulla' ( 4 ) , adipose tissue ( 2 ) , heart ( 2 ) , intestine ( 2 ) , liver ( 2 , 3 ) , lung ( 2 ) , muscle ( 2 ) , pancreas ( 2 ) , PC-12 (chromaffin) [TrkA (rat), transfection] ( 1 ) , PC-12 (chromaffin) ( 1 ) , spleen ( 2 ) , stomach ( 2 )

Upstream Regulation
Treatments:	PDGF ( 1 )

References
1	Biarc J, Chalkley RJ, Burlingame AL, Bradshaw RA (2012) The induction of serine/threonine protein phosphorylations by a PDGFR/TrkA chimera in stably transfected PC12 cells. Mol Cell Proteomics 11, 15-30 22027198 Curated Info
2	Lundby A, et al. (2012) Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. Nat Commun 3, 876 22673903 Curated Info
3	Demirkan G, et al. (2011) Phosphoproteomic Profiling of In Vivo Signaling in Liver by the Mammalian Target of Rapamycin Complex 1 (mTORC1). PLoS One 6, e21729 21738781 Curated Info
4	Hoffert JD, et al. (2006) Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites. Proc Natl Acad Sci U S A 103, 7159-64 16641100 Curated Info