Thr503

Site Information
sPPPsPItEAsEAAE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 483444

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 , 5 )
Disease tissue studied:	anthrax infection ( 2 ) , melanoma skin cancer ( 5 )
Relevant cell line - cell type - tissue:	'fat, brown' ( 3 ) , heart ( 3 ) , kidney ( 3 ) , liver ( 3 ) , lung ( 3 ) , MEF (fibroblast) [p53 (mouse), homozygous knockout] ( 1 ) , mpkCCD (renal) ( 4 ) , pancreas ( 3 ) , skin [mGluR1 (mouse), transgenic, TG mutant mice] ( 5 ) , spleen ( 2 , 3 ) , testis ( 3 )

References
1	Hsu PP, et al. (2011) The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science 332, 1317-22 21659604 Curated Info
2	Manes NP, et al. (2011) Discovery of mouse spleen signaling responses to anthrax using label-free quantitative phosphoproteomics via mass spectrometry. Mol Cell Proteomics 10, M110.000927 21189417 Curated Info
3	Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89 21183079 Curated Info
4	Rinschen MM, et al. (2010) Quantitative phosphoproteomic analysis reveals vasopressin V2-receptor-dependent signaling pathways in renal collecting duct cells. Proc Natl Acad Sci U S A 107, 3882-7 20139300 Curated Info
5	Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26 19367708 Curated Info