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Home > Phosphorylation Site Page: > Ser428  -  NEDD4L (human)

Site Information
AEDGASGsATNSNNH   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 487434

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Regulatory protein:
Akt1 (human) ( 1 ) , SGK1 (human) ( 1 )

Downstream Regulation
Effects of modification on NEDD4L:
activity, inhibited ( 1 )



Lee IH, et al. (2007) Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2. J Biol Chem 282, 29866-73
17715136   Curated Info