Tyr812
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.7.1.1
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Tyr812  -  gp130 (mouse)

Site Information
EILPRQPyFKQNCsQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450054

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
chondrocyte ( 1 ) , fibroblast ( 1 ) , splenocyte ( 1 )

Upstream Regulation
Treatments:
development ( 1 ) , IL-11 ( 1 ) , IL-6 ( 1 ) , LIF ( 1 ) , oncostatin_M ( 1 ) , R805 ( 1 )

Downstream Regulation
Effects of modification on biological processes:
signaling pathway regulation ( 1 ) , transcription, altered ( 1 )

References 

1

Shkhyan R, et al. (2023) Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis. Sci Transl Med 15, eabq2395
36947594   Curated Info