Ser741
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Home > Phosphorylation Site Page: > Ser741  -  Kit (human)

Site Information
TkADkRRsVRIGsyI   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450035

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 ) , phosphoamino acid analysis ( 1 )
Relevant cell line - cell type - tissue:
PAE (endothelial) ( 1 )

Upstream Regulation
Kinases, in vitro:
PKCA (human) ( 1 )
Treatments:
SCF ( 1 )

Downstream Regulation
Effects of modification on Kit:
enzymatic activity, inhibited ( 1 ) , phosphorylation ( 1 )

References 

1

Blume-Jensen P, Wernstedt C, Heldin CH, Rönnstrand L (1995) Identification of the major phosphorylation sites for protein kinase C in kit/stem cell factor receptor in vitro and in intact cells. J Biol Chem 270, 14192-200
7539802   Curated Info