Thr421

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Home > Phosphorylation Site Page: > Thr421 - PAK3 (rat)

Site Information
PEQSKRstMVGTPYW SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 448126

In vivo Characterization
Methods used to characterize site in vivo:	electrophoretic mobility shift ( 1 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:	COS (fibroblast) ( 1 ) , HeLa (cervical) ( 1 )

Upstream Regulation
Kinases, in vitro:	PAK3 (rat) ( 1 )

Downstream Regulation
Effects of modification on PAK3:	enzymatic activity, induced ( 1 )

References
1	Chong C, Tan L, Lim L, Manser E (2001) The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity. J Biol Chem 276, 17347-53 11278486 Curated Info

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