Lys295
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Home > Acetylation Site Page: > Lys295  -  HSP90A (mouse)

Site Information
QEELNktkPIWTRNP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 486377

In vivo Characterization
Methods used to characterize site in vivo:
immunoassay ( 1 ) , immunoprecipitation ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
neuron-brain ( 1 ) , RN46A (embryonic) ( 1 )

Upstream Regulation
Treatments:
ACY-738 ( 1 ) , Tubastatin A ( 1 )

Downstream Regulation
Effects of modification on HSP90A:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Induce interaction with:
FKBP5 (human) ( 1 )
Inhibit interaction with:
FKBP4 (human) ( 1 )

References 

1

Jochems J, et al. (2015) Enhancement of stress resilience through histone deacetylase 6-mediated regulation of glucocorticoid receptor chaperone dynamics. Biol Psychiatry 77, 345-55
25442004   Curated Info