Lys527
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Home > Sumoylation Site Page: > Lys527  -  Myb (human)

Site Information
PPLLKKIkQEVEsPt   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 486352

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 2 ) , immunoprecipitation ( 2 ) , mass spectrometry ( 1 ) , modification-specific antibody ( 2 ) , mutation of modification site ( 2 ) , western blotting ( 2 )
Disease tissue studied:
leukemia ( 2 ) , T cell leukemia ( 2 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on Myb:
intracellular localization ( 2 ) , sumoylation ( 2 )
Effects of modification on biological processes:
transcription, inhibited ( 2 )

References 

1

Tammsalu T, et al. (2014) Proteome-wide identification of SUMO2 modification sites. Sci Signal 7, rs2
24782567   Curated Info

2

Dahle Ø, et al. (2003) Transactivation properties of c-Myb are critically dependent on two SUMO-1 acceptor sites that are conjugated in a PIASy enhanced manner. Eur J Biochem 270, 1338-48
12631292   Curated Info