Ser2366
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Home > Phosphorylation Site Page: > Ser2366  -  p300 (human)

Site Information
MEQGHFAsPDQNSML   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 486264

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
ERK2 (human) ( 1 )
Kinases, in vitro:
ERK2 (human) ( 1 )
Treatments:
EGF ( 1 ) , U0126 ( 1 )

Downstream Regulation
Effects of modification on p300:
enzymatic activity, induced ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, altered ( 1 )

References 

1

Chen YJ, Wang YN, Chang WC (2007) ERK2-mediated C-terminal serine phosphorylation of p300 is vital to the regulation of epidermal growth factor-induced keratin 16 gene expression. J Biol Chem 282, 27215-28
17623675   Curated Info