Thr278

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Home > Phosphorylation Site Page: > Thr278 - NBS1 (mouse)

Site Information
VDVGITNtQLIISHS SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 449968

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	MEF (fibroblast) ( 1 )

Upstream Regulation
Putative in vivo kinases:	ATM (human) ( 1 )

Downstream Regulation
Effects of modification on biological processes:	DNA repair, induced ( 1 )

References
1	Li T, Wang ZQ (2011) Point mutation at the Nbs1 Threonine 278 site does not affect mouse development, but compromises the Chk2 and Smc1 phosphorylation after DNA damage. Mech Ageing Dev 132, 382-8 21664921 Curated Info

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