Thr201
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Home > Phosphorylation Site Page: > Thr201  -  JIP1 (mouse)

Site Information
PLKTGEQtPPHEHIC   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 449954

In vivo Characterization
Methods used to characterize site in vivo:
[32P] ATP in vitro ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
neuroblastoma ( 1 )
Relevant cell line - cell type - tissue:
'neuron, cortical' ( 1 ) , brain ( 1 ) , SH-SY5Y (neural crest) ( 1 )

Upstream Regulation
Putative in vivo kinases:
CDK5 (human) ( 1 )
Kinases, in vitro:
CDK5 (mouse) ( 1 )

Downstream Regulation
Effects of modification on JIP1:
phosphorylation ( 1 ) , ubiquitination ( 1 )
Effects of modification on biological processes:
cell growth, induced ( 1 )

References 

1

Im DS, et al. (2022) Cdk5-mediated JIP1 phosphorylation regulates axonal outgrowth through Notch1 inhibition. BMC Biol 20, 115
35581583   Curated Info

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